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Record 1 of 1 for the search Author R. Cepeda; Facultad de Ciencias Veterinarias y Pecuarias, Departamento de Ciencias Básicas, Universidad de Chile 

Efecto antivascular de vincristina en tumor venéreo transmisible del canino

C.M. Gonzalez; Facultad de Ciencias Veterinarias y Pecuarias, Departamento de Patología Animal, Universidad de Chile
R. Cepeda; Facultad de Ciencias Veterinarias y Pecuarias, Departamento de Ciencias Básicas, Universidad de Chile
E. Flores; Facultad de Ciencias Veterinarias y Pecuarias, Departamento de Ciencias Clínicas, Universidad de Chile
G. Cattaneo; Facultad de Ciencias Veterinarias y Pecuarias, Departamento de Ciencias Clínicas, Universidad de Chile
Francisco Contreras; Facultad de Ciencias Veterinarias y Pecuarias, Universidad de Chile

2006

  • Edition Avances en Ciencias Veterinarias; Vol. 21, No. 1-2 (2006): Enero-Diciembre
    Universidad de Chile
  • Type Libro
  • Subject Transmisible venereal tumor, vascularization, vincristine
  • Description
    Among the more investigated antineoplastic therapeutic options, the anti - angiogenic therapy has no important collateral effects for the patient. This therapy targets the factors implied in the progress of the angiogenic cascade, to impede the vascular support of tumoral tissue, increasing the apoptosis of the neoplastic cells.In this study the chang ...
    Among the more investigated antineoplastic therapeutic options, the anti - angiogenic therapy has no important collateral effects for the patient. This therapy targets the factors implied in the progress of the angiogenic cascade, to impede the vascular support of tumoral tissue, increasing the apoptosis of the neoplastic cells.In this study the changes of the vascularization of canine venereal transmissible tumor (CTVT) were studied, both in the progressive phase of growth and during regression induced by treatment with vincristine sulphate (VCR). This antineoplastic drug apart from its cytostatic effect on tumors, it has demonstrated direct antivascular effect.Histopathologically with Papanicolau stain, was observed that after the treatment, the number of blood vessels diminished significantly (p
    Facultad de Ciencias Veterinarias y Pecuarias
  • Identifier 34380